FIND A BIOALPS ACTOR

Merging the fields of biology, technology, and medicine

The rapid growth in data is astounding in terms of volume, speed, veracity and variety of data sources from genome sequencing experiments, biological and biomedical imaging that generate large volumes of data. The ability to store, process, analyse and view this data is gaining momentum in the Western Switzerland‘s healthcare industry. The Swiss phar maceutical industry recognises that bioinformatics is crucial for validating potential drug targets and for determining which ones are the most suitable for entering the drug development pipeline1.

THE USE OF BIOINFORMATICS IN DRUG DISCOVERY COULD REDUCE THE R&D COSTS FOR NEW DRUGS BY 50%. SWITZERLAND HAS THE HIGHEST CONCENTRATION OF BIOINFORMATICIANS WORLDWIDE.

Switzerland is among the top ten industrialised countries in the world in terms of ICT readiness and one of the big data development hubs for life sciences2. The global bioinformatics market ac counted for $4.2 billion in 2014 and is poised to reach $13.3 billion by 2020 with a CAGR of 20.9% from 2015 to 20203 driven by the increasing use of bioinformatics in drug discovery and biomarkers development processes which could lead to a reduction in R&D costs for new drugs by 50%4. Switzerland has the highest concentration of bio informaticians worldwide.

The Swiss Institute of Bioinformatics (SIB) whose services, software tools and databases are used worldwide by researchers in life sciences with more than 900,000 requests per month, created the first web server in life sciences known as ExPASY.

The Human Brain Project (HBP)5, a 10-year scientific research project, established in 2013, fed erates hundreds of researchers, from 112 partner institutions in 24 countries, is coordinated by the Swiss Federal Institute of Technology in Laus anne (EPFL). The HBP enables data sharing, reconstruction of the brain at different biological scales and the development of brain-inspired computing systems.

The Lausanne Institutional Biobank (BIL) is currently developing Europe’s largest biobank with biological samples donated by the general pop ulation. A bioresource for research purposes, sequencing is being used to understand population-based medicine and move towards personalised medicine.

“Big Data” has proliferated Western Switzerland’s bioinformatics companies such a s Sophia Genetics and Quartz Bio that specialise in outsourcing services such as sequencing or prospecting for disease-specific biomarkers into a pre dictive tool.

BioAlps region brings together more than 1000 people as big data practitioners, research ers, students, clinicians, health IT experts, and data scientists to improve the state of our healthcare systems.

Western Switzerland, yet again, is demonstrating that it is a hotbed of innovation and excellence by delivering on the promise with big data infrastructure investments and tools of the highest scientific standards.

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SIB SWISS INSTITUTE OF BIOINFORMATICS

The Swiss Institute of Bioinformatics (SIB) is an academic, non-profit foundation established by leading researchers in 1998 with the backing of a few visionary Swiss politicians. With offices on the campus of the University of Lausanne (UNIL), SIB is at the frontier of life science and computer science. The organisation provides high quality bioinformatics resources and services to the national and international life science community and coordinates research and education in bioinformatics throughout Switzerland.

Through its bioinformatics core facilities, high-performance computing centres, and embedded bioinformaticians, SIB provides expert data analysis services and computing power to Swiss and international life scientists, thus enabling them to perform biomedical research and analyse the resultant data. SIB provides continuing education in bioinformatics.

SIB has 16 institutional members, which span all the major universities of Switzerland and other research institutions. Its 56 research and service groups develop, maintain and provide core bioinformatics resources for all areas of the life sciences. SIB belongs to several prestigious international networks, such as the Global Alliance for Genomics and Health and the European Life Science Infrastructure for Biological Information (ELIXIR).

Brains, data and the life sciences – a strong cocktail in the bioalps region

Working hand in hand with companies, the research institutions in Western Switzerland provide a wealth of big data knowledge and bioinformatics tools that span all disciplines of the life sciences, not just human health.

The non-exhaustive lists below showcase some examples of the work being done in the region.

Find more information in our extensive databases: www.bioalps.org/community and, for the six Alpine regions, www.alpslifesciencesearch.com

Academic institutions at the forefront of big data and bioinformatics in western Switzerland

University of Lausanne UNIL

Swiss Institute of Bioinformatics (SIB)

High quality bioinformatics resources and services

University Hospital
of Lausanne CHUV

Department of Laboratories Lausanne Institutional Biobank (BIL)

DNA biobank for genetic research

University of Geneva UNIGE

SIB, computing sciences

Basic research, evolutionary genetics and phylogenetics.

University Hospitals of Geneva HUG

School of medicine, department of genetics and evolution

Ecole Polytechnique Fédérale de Lausanne EPFL

SIB

High quality bioinformatics resources and services

Brain Mind Institute (BMI)

Blue Brain Project

University of Fribourg UNIFR

SIB Department of medicine

Sports modelling, artificial intelligence

University of Bern UNIBE

SIB Department of medicine

Genome analysis, modelling

University of Applied Sciences Western Switzerland HES-SO

Geneva -Department of Information sciences

Computing research

Valais - Institute of Business Information Systems

Content-based medical image retrieval

Ludwig Institute for Cancer Research

SIB

Brain cancer

Haute Ecole d’ingéniérie
et de Gestion HEIG-VD

Biomedical engineering group

Biomedical data mining

Sampling list of large and small biomaterials companies in the Bioalps cluster

1DROPDIAGNOSTICS
Dosage for prescription based on patent’s medical history and biological parameters stored on a remote databank

GENOHM
Laboratory Information Management System (LIMS)

AARDEX
Cloud-based platform to measure and monitor patient adherence to medication

GENOMSYS
Solution and systems for efficient genomic information processing

CEREBRO
Cloud platform for quality control and benchmarking of imaging biomarkers

PRECISION FOR MEDECINE
Biomarker technological platforms such as genetics, transcriptomics, protein assays and cellular assays

CYTEL
Statistical software for designing every type of clinical trial, including adaptive designs

SAPHETOR
Data-driven solutions based on NGS for precision medicine (cancer, rare & cognitive diseases)

DATA MINING INTERNATIONAL
Data management, data extraction and data analysis

SIMPLICITYBIO
In-silico biomarker diagnostics based on genomics and proteomics

DRUGDESIGNTECH
Knowledge management and decision support for both biologic therapeutics and traditional small molecule drug discovery

SMARTGENE
Genetic sequencing data-managment software solutions for medical research and clinic diagnostics

GENEBIO
Multifaceted informatics for the life sciences; commercializes products developed by the SIB

SOPHIA GENETICS
Software modules covering bioinformatic analysis genetic tests results and patient DNA sequence data through safe storage and sharing

The fact sheet provides a view of the key players in the sector at any given time; it is not comprehensive and is subject to regular updates.
This current edition was produced in Spring 2018.

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