FIND A BIOALPS ACTOR

A proficient network of knowhow to grow international markets

Bioservice companies are part of the rich fabric of the life sciences in the Western Switzerland region, providing valuable expertise and knowhow.

Bioservices span the full business range from clini cal research organisations (CROs) to next gen eration sequencing (NGS), through laboratories, clinical development and intellectual property consultants, to legal and financial specialists. The BioAlps region offers all the services inherent in bringing a product from idea to market, within easy reach.

THE STRENGTHOF THE WESTERN SWITZERLAND REGION LIES INITS TIGHTLY KNIT COMMUNITY, AS WELL AS THE WIDE-RANGING INTERNATIONAL EXPERIENCE OF BOTH SCIENTISTS AND PROFESSIONALS INTERACTING WITH THE ALL SERVICES.

The strength of the Western Switzerland region lies in its tightly knit community, as well as the wideranging international experience of both scientists and professionals interacting with technology transfer offices, intellectual property consultants, manufacturing, research and clinical services hosted by the cluster. The academic life sciences core facilities in Geneva, Lausanne and Neuchâtel comprise state-of-the-art imaging Bioservices A pro­cient network of knowhow to grow international markets ing, genomics, bioinformatics, proteomics, animal models, clinical and epidemiological studies, biomolecular screening, flow cytometry, protein expression and chemical analysis. The University Hospitals of Geneva, Lausanne and Bern participateinnumerous clinical trials sponsored by Swiss and international companies. All the academic institutions encourage innovation, and several have set up innovation parks to promote start-ups and spins, such as the Innovation Park (PSE) in the Ecole polytechnique fédérale de Lausanne (EPFL). Other innovation parks such as Eclosion in Geneva, Y-Parc in Vaud, Neode in Neuchâtel, and the Ark in Valais are sponsored by the cantons.

The life science industry has access to Contract Research Organisations (CROs) in the BioAlps cluster, such as Frimorfo, SOCAR Research and Covance, which provide the full range of services from pre-clinical research to large scale international clinical trials. Contract Manufacturing companiessuchas Baccinex,BASFor Lonza each have a specialised area of activity,o‑eringthe life science industry world-class research, development and manufacturing from preclinical to commercial quantities. Beyond such multinational service companies, the BioAlps region also hosts intellectual property, patent, merger and acquisition, legal, financial and other experts and consultants, spanning disciplines and technologies for the greater benefit of the life sciences. At the same time, start-ups such as Sophia Genetics are leveraging the new opportunities that next generation sequencing (NGS) offer, while more mature companies such as GeneBio offer Mass Spectrometry characterisation of proteins and small molecules as well as proteome imaging.

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BACCINEX: LOCATION ENABLES FILL/ FINISH CONTRACT MANUFACTURING FOR THE WHOLE WORLD

Managed by Dr Ursula Bausch, Baccinex was founded in 1999 in the Canton of Jura and GMP certified in 2004. Specialised in freeze-drying and liquid sterile dosage forms for clinical trialsfor biotech and pharmaceutical development companies, Baccinex operates as a contract manufacturing organization for aseptic filling (vials and ampoules), lyophilization, terminal sterilisation, clinical packaging (randomized labelling), quality control release testing, stability studies(and stability storage according to ICH conditions), GMP storage, and development activities (scaleup, formulation, freeze drying cycle development, GMP consulting).

The company has a strong expertise in scaling up projects for commercialisation, notably in fill/finish and lyophilisation of small molecules and biological productsin vials and ampoules. Baccinex’s facilities and cold storage allow GMP storage of primary materials and finished products. Baccinex processes about 50-60 different clinical projects each year and produces products for commercialization too. The company’s geographic location in the BioAlps region enables it to organise worldwide shipments of samples, finished products or clinical trial supplies.

A pool of experienced and highly qualified professionals

From idea to worldwide markets, the BioAlps region hosts research institutions, teaching and research hospitals, technology centres, service companies and expert consultants who all provide an environment conducive to research and development. The “can do” attitude of entrepreneursto harness the wide array of expertise offers unparalleled prospectsfor those in search of opportunity.

The lists below are non exhaustive and showcase some examples of the work being done in the region. Find more information in our extensive databases: www.bioalps.org/community and, for the six alpine regions, www.alpslifesciencesearch.com

Academic institutions at the forefront of bioservices in western switzerland

To access the whole range of bioplatforms within the region’s academic institutions:

Ecole Polytechnique fédérale
de Lausanne EPFL

Technology Transfer Organisms: TTO EPFL

University of Fribourg UNIFR

TechTransfer Fribourg

University of Neuchâtel UNINE

TT Neuchâtel

University Hospital of Lausanne CHUV
University of Lausanne UNIL

PACTT Technology Transfer UNIL-CHUV

University of Geneva UNIGE
University Hospitals of Geneva HUG
University of Applied Sciences HES-SO

UNITEC (UNIGE & HUG & HES-SO Geneva)

Swiss Center for Electronics and
Microtechnology CSEM

Technology Transfer CSEM

University of Bern and
Bern University Hospital (Inselspital)
UNIGE and HUG
UNIL and CHUV

Clinical Trials Units
Clinical Research Center (CRC)
Clinical Research Center (CRC)
Clinical epidemiology center (Cepic)

Swiss Institute of Bioinformatics SIB

Bioinformatics resource portal ExPASy

University of Fribourg UNIFR

Fribourg Center for Nanomaterials (FriMat)Adolph Merckle Institute (AMI)

University of Lausanne UNIL

Vaccine Formulation Laboratory
World Health Organization
(WHO) Collaborating Centre

University of Applied Sciences Western
Switzerland (HEPIA / HES-SO)

Bio-engineering, micro devices for diagnostic

University of Applied Sciences Western
Switzerland (ITV / HES-SO Valais)

Microbiological, biochemical and genetic analyses process and methods validation, biomass / biomolecules production, peptide and proteins technologies

Sampling list of large and small bioservice companies in the Bioalps cluster

BACCINEX
Fill and finishing of sterile lyophilized or liquid dosage forms

LONZA
Biotechnology and pharmaceutical products, services, and research

BACHEM
Process and manufacturing of peptides and complex organic molecules (APIs)

NV LOGISTICS
Worldwide life science logistics management

COVANCE
Biotech and pharmaceutical drug development services

PIXON ENGINEERING
Process development through the engineering, up to the execution with its final qualification / validation

CELLNTEC
Innovative culture media, 2D and 3D in vitro models

PRECLIN BIOSYSTEMS
In vivo preclinical testing platform for the identification and validation of lead candidate therapeutics

EPITHELIX
In vitro human reconstituted human respiratory cells for research

SELEXIS
Drug discovery, cell line development and scale-up to manufacturing

EXCELLGENE
Services in the field of improved processing from gene to large scale manufacturing of proteins

SOCAR RESEARCH
Integrated and comprehensive services for the design, management and conduct of phase I /IV clinical trials

FASTERIS
Next-generation and Sanger DNA sequencing services

SOPHIA GENETICS
Bioinformatics analysis, visualization and banking of patient NGS data

FRIMORFO
Preclinical contract research organization: efficacy studies and genotyping

SWISSFILLON
Automated filling line for vials, syringes and cartridges

GENEBIO
Software for characterizing small molecules, proteomics, proteins database and flow

UNILABS
Complete laboratory analysis services from sampling to testing and analysis

INTERLABOR BELP
Chemical, physical, microbiological and molecular-biological analyses

VALTRONIC
Provider of engineering, industrialization and manufacturing for Class II & III medical devices

The fact sheet provides a view of the key players in the sector at any given time; it is not comprehensive and is subject to regular updates.
This current edition was produced in Spring 2018.